According to the website of http://unilife.jp , the raw material of MMNT is from US, and the inventor is Dr.Patrick Flanagan. Therefore, I perform some searching on internet in order to understand more about Dr. Patrick Flanagan's paper. I managed to find a journal written by Dr. Patrick through wikipedia. Here is the link to the journal:
http://www.sciencedirect.com/science/article/pii/S0360319902002860
If you are good in chemistry, you may understand what is written in that journal.
Abstract from above journal
Synthesis
of an anionic hydride from monomeric silsesquioxanes is described. The
novel compound, dubbed “silica hydride” is the first of several newly
synthesized compounds from an interstitially embedded hydride family. It
is a hydride-based compound with H− ions interstitially
embedded in a matrix of caged silica. This compound exhibits profoundly
different characteristics than other known compounds in hydride family.
Unlike saline hydrides, the silica hydride demonstrates no overt or
violent reaction with water or air. However it is capable of generating
aqueous reductive potential readings of
for extended time periods. In vitro biological testing demonstrated no
cytotoxicity induced by the compound while demonstrating efficacy as an
antioxidant. In vivo studies of the compound have shown that it has a
significant ability to reduce lactic acid build up in muscles by
one-half after exercise. The synthesis of the silica hydride resulted in
an approximately 16.8% w/w hydride content, as determined by density
changes, proton NMR spectroscopy and ion beam analyses. Scanning and
tunneling electron microscopy, Rutherford backscattering spectroscopy
(RBS), forward recoil (FReS) ion beam analyses, in addition to Fourier
transform infrared spectroscopy, reduction potential and CP-MAS solid state NMR were additionally used to characterize the compound.
Continue reading in http://www.sciencedirect.com/science/article/pii/S0360319902002860
Continue reading in http://www.sciencedirect.com/science/article/pii/S0360319902002860
Conclusion from journal
The
novel siliceous compound acts as a colloidal carrier for the very small
hydride anions that are released in an aqueous solution. This nanosized
colloidal bioencapsulated compound could be an incredibly effective
radical scavenger and aid in the reduction of oxidative stress due to
its minimal size and high reduction potential.
This
novel compound presented in this paper has demonstrated promising in
vitro and in vivo biochemical significance with uses including reducing
agents, antioxidants and nutritional supplementation. The synthesis is
simple and efficient with consistent results of about 17% w/w hydride
content with respect to the starting compound. Biologically friendly
compounds that incorporate health-beneficial minerals, such as silica,
with the scavenging and reducing capabilities of a hydride provide for
numerous possibilities of uses. This technique has proven valid for
creating hydrides out of other non-metallic, compounds, such as
carbonate. The continuation of studies on this new family of hydride
compounds could prove invaluable in biochemical, medicinal and
analytical venues.
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